Bloomington-based Fasikl is on a mission to improve the lives of 7 million people in the U.S. living with essential tremor, a neurological movement disorder that causes involuntary muscle quivering that can interfere with everyday activities. It can happen spontaneously, as an isolated condition, or be a symptom of other disorders such as multiple sclerosis and Parkinson’s disease.

CEO Zhi Yang says his startup uses artificial intelligence to personalize and improve treatments for essential tremor, which is about seven times more common than Parkinson’s, according to the National Institutes of Health.

After working for a year with the University of Minnesota Technology Commercialization, which connected Yang with investors and business leaders, he co-founded Fasikl in 2019. During the Covid-19 pandemic, he developed the Felix NeuroAI Wristband for people with essential tremor. The device delivers electrical stimulation to nerves at the wrist to modulate neural activity throughout.

Felix consists of the wrist-worn device, a smartphone application that communicates with the device and the cloud, and the cloud-based AI system that analyzes patient data and adjusts stimulation patterns in real time.

“This allows the treatment to become personalized and adaptive to each individual rather than delivering the same therapy to everyone,” Yang says.

Felix is prescription-only. It became available following FDA clearance in 2025 and is covered by Medicare.

To date, Fasikl has raised more than $60 million. It closed a fundraising round in 2025 with more than $26 million raised, which has supported commercial expansion, additional clinical programs, and continued investment in its AI platform. “If, years from now, people can point to AI therapeutics as a safe, effective, and widely accepted form of healthcare,” Yang says, “then I would consider that our greatest accomplishment.”

HQ: Bloomington
Founded: 2019
Founder: Zhi Yang