John Noseworthy

CEO

Mayo Clinic

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Mayo Clinic CEO John Noseworthy says the giant health care provider has made it through the troubled waters of health care reform in good shape and is now “ready to play offense” as it aggressively seeks to stay competitive on the highest national level. One of Noseworthy’s key initiatives is pouring resources into medical research—some $276 million in internal funding was spent in 2014—made possible in part by his successful efforts to increase Mayo’s profit margin from 4.3 percent in 2009 to last year’s 8.5 percent.