Sonodynamic therapy, Alpheus Medical’s novel brain cancer treatment, starts with an FDA-approved drug that accumulates in cancer cells. “We’re able to bathe the whole brain with ultrasound,” explains founder Vijay…
The TCB 100 - 2026
The TCB 100 is the list of all lists, the essential guide to people in and around Minnesota business likely to make news and drive change in the year ahead.
Written by Madison Bloomquist, Peter Diamond, Liz Fedor, Shawn Gilliam, Justine Jones, Kelly Kegans, Sarah Lutman, Stephanie March, Steve Marsh, Madeline Nachbar, Jayne Haugen Olson, Adam Platt, Varad Raigaonkar, Gene Rebeck, and Erik Tormoen
In a year when most high-profile Minnesota companies have struggled or underperformed, Life Time tells a different tale. TCB’s cover story this past February outlined how the company, led by…
Chanda Smith Baker became president and CEO of the Saint Paul and Minnesota Foundation in August. She brings deep nonprofit leadership experience as well as family roots in both St.…
The culinary idea behind Razava is to recapture the nutritious, time-intensive purity of handmade sourdough. The geographic idea is to join the commercial comeback of Grand Avenue, injecting ideas that…
Extraordinary possibility—that’s what Gensler’s Bill Baxley sees in Minneapolis’ urban core. “How can it be more inclusive, and how can we use the power of design to pull us together?”…
Beardsley took the helm of what he calls “Minnesota’s world port” in May after more than a decade as its CFO. Two years ago, the Duluth-Superior Port launched a transatlantic…
After a 24-year career at 3M, including running its corporate venture capital arm in Asia, Michelle Bellanca made a major career change. “I had a passion for the startup world…
An October Bloomberg article estimated that there are 19,000 private equity funds in the U.S. (compared with 14,000 McDonald’s restaurants, so yes, it’s a lot). How does a newcomer like…
Cub’s owner, food wholesaler UNFI, finally got wise this year and hired a local to run its largest and somewhat underperforming subsidiary. David Best is a Target and General Mills…
Cancer continues to be one of the most serious and most confounding diseases that medical science battles. Plymouth-based HistoSonics is developing a promising new weapon. It harnesses an ultrasound technology…
Alison Rempel Brown assumed the top job at the Science Museum of Minnesota in 2016 in a very different political climate. In 2026, she says one of her priorities is…
Minneapolis-based Rise and Shine is one of the country’s fastest-growing ad agencies, and Matt Burgess is a key reason why. He returned to the Twin Cities in mid-2022 after six…
Twenty-three years after founding Jefferson Capital, Burton oversaw the Minneapolis-based company’s IPO in June. Jefferson buys receivables from banks, auto finance companies, and other consumer lenders in the U.S., Canada,…
Matt Caldwell is a Staten Island native, the son of a New York City cop, a West Point and Kellogg School of Business graduate, who cut his teeth in finance…
In her seven years with the Minnesota Lynx, Napheesa "Phee" Collier has established herself as one of the best basketball players in the world: defensive player of the year, multiple…
NTH is a bit of a unicorn in commercial real estate, focused as much on advising and strategic planning as transactions. Anna Coskran, its new president, is just its third…
Most of the companies this Wayzata-based venture capital firm owns or invests in are small and midsize Minnesota businesses. What makes Traction Capital distinctive, Cox says, is that “we mentor…
Andre Creighton credits his success to the teamwork instilled by playing high school and college sports. Starting his career in public accounting, Creighton went on to earn his MBA from…